Assistant Professor:Ryoichi Sugisawa
Assistant Professor:Ryoichi Sugisawa
Education
2017 | Ph.D., Laboratory of Molecular Biomedicine for Pathogenesis, Center for Disease Biology and Integrative Medicine, Faculty of Medicine, The University of Tokyo (Supervisor: Dr. Toru Miyazaki) |
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2013 | BVetMed., School of Veterinary Medicine, Faculty of Veterinary Science, Nippon Veterinary and Life Science University |
Work experience
2023-present | Assistant Professor, Department of Biochemistry, Kindai University Faculty ofMedicine |
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2017-2023 | Research Fellow, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Ireland (Prof. Andrew G Bowie lab) |
2017 | Project Assistant Professor, Faculty of Medicine, The University of Tokyo |
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Selected publications
Doran, CG., Sugisawa, R., Carty, M., Roche, F., Fergus, C., Hokamp, K., Kelly, VP. and
Bowie, AG. CRISPR/Cas9-mediated SARM1 knockout and epitope tagged mice reveal that
SARM1 does not regulate nuclear transcription, but is expressed in macrophages. JBC.
16;297(6):101417. (2021) DOI: 10.1016/j.jbc.2021.101417
Carty, M., Kearney, J., Shanahan, KA., Hams, E., Sugisawa, R., Connolly, D., Doran, CG.,
Muñoz-Wolf, N., Gürtler, C., Fitzgerald, KA., Lavelle, EC., Fallon, PG. and Bowie, AG. Cell
survival and cytokine release after inflammasome activation is regulated by the Toll-IL-1R
protein SARM. Immunity. 18;50(6), 1412-1424. (2019) DOI: 10.1016/j.immuni.2019.04.005
Sugisawa, R., Komatsu, G., Hiramoto, E., Takeda, N., Yamamura, K., Arai, S. and Miyazaki,
T. Independent modes of disease repair by AIM protein distinguished in AIM-felinized mice.
Sci Rep. 8, 13157. (2018) DOI: 10.1038/s41598-018-31580-6
Sugisawa, R., Hiramoto, E., Matsuoka, S., Iwai, S., Takai, R., Yamazaki, T., Mori, N., Okada,
Y., Takeda, N., Yamamura, K., Arai, T., Arai, S. and Miyazaki, T. Impact of feline AIM on the
susceptibility of cats to renal disease. Sci Rep. 6: 35251. (2016) DOI: 10.1038/srep35251
Arai, S., Kitada, K., Yamazaki, T., Takai, R., Zhang, X., Tsugawa, Y., Sugisawa, R.,
Matsumoto, A., Mori, M., Yoshihara, Y., Doi, K., Maehara, N., Kusunoki, S., Takahata, A.,
Noiri, E., Suzuki, Y., Yahagi, N., Nishiyama, A., Gunaratnam, L., Takano, T. and Miyazaki, T.
Apoptosis inhibitor of macrophage protein enhances intraluminal debris clearance and
ameliorates acute kidney injury in mice. Nat Med. 22: 183-193. (2016) DOI:
10.1038/nm.4012