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Assistant Professor:Ryoichi Sugisawa

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Assistant Professor:Ryoichi Sugisawa

 Assistant Professor:Ryoichi Sugisawa

Education

 2017 Ph.D., Laboratory of Molecular Biomedicine for Pathogenesis, Center for Disease Biology
and Integrative Medicine, Faculty of Medicine, The University of Tokyo (Supervisor: Dr. Toru
Miyazaki)
 2013 BVetMed., School of Veterinary Medicine, Faculty of Veterinary Science, Nippon
Veterinary and Life Science University
   

Work experience

 2023-present Assistant Professor, Department of Biochemistry, Kindai University Faculty ofMedicine
2017-2023  Research Fellow, School of Biochemistry and Immunology, Trinity Biomedical
Sciences Institute, Trinity College Dublin, Ireland (Prof. Andrew G Bowie lab) 
2017  Project Assistant Professor, Faculty of Medicine, The University of Tokyo

 

 

Selected publications

 

 Doran, CG., Sugisawa, R., Carty, M., Roche, F., Fergus, C., Hokamp, K., Kelly, VP. and
Bowie, AG. CRISPR/Cas9-mediated SARM1 knockout and epitope tagged mice reveal that
SARM1 does not regulate nuclear transcription, but is expressed in macrophages. JBC.
16;297(6):101417. (2021) DOI: 10.1016/j.jbc.2021.101417

Carty, M., Kearney, J., Shanahan, KA., Hams, E., Sugisawa, R., Connolly, D., Doran, CG.,
Muñoz-Wolf, N., Gürtler, C., Fitzgerald, KA., Lavelle, EC., Fallon, PG. and Bowie, AG. Cell
survival and cytokine release after inflammasome activation is regulated by the Toll-IL-1R
protein SARM. Immunity. 18;50(6), 1412-1424. (2019) DOI: 10.1016/j.immuni.2019.04.005

Sugisawa, R., Komatsu, G., Hiramoto, E., Takeda, N., Yamamura, K., Arai, S. and Miyazaki,
T. Independent modes of disease repair by AIM protein distinguished in AIM-felinized mice.
Sci Rep. 8, 13157. (2018) DOI: 10.1038/s41598-018-31580-6

Sugisawa, R., Hiramoto, E., Matsuoka, S., Iwai, S., Takai, R., Yamazaki, T., Mori, N., Okada,
Y., Takeda, N., Yamamura, K., Arai, T., Arai, S. and Miyazaki, T. Impact of feline AIM on the
susceptibility of cats to renal disease. Sci Rep. 6: 35251. (2016) DOI: 10.1038/srep35251

Arai, S., Kitada, K., Yamazaki, T., Takai, R., Zhang, X., Tsugawa, Y., Sugisawa, R.,
Matsumoto, A., Mori, M., Yoshihara, Y., Doi, K., Maehara, N., Kusunoki, S., Takahata, A.,
Noiri, E., Suzuki, Y., Yahagi, N., Nishiyama, A., Gunaratnam, L., Takano, T. and Miyazaki, T.
Apoptosis inhibitor of macrophage protein enhances intraluminal debris clearance and
ameliorates acute kidney injury in mice. Nat Med. 22: 183-193. (2016) DOI:
10.1038/nm.4012