377-2 Ohno-Higashi, Osaka-Sayama, Osaka 589-8511, Japan
Tel +81-72-366-0221
Fax +81-72-366-0245
E-mail seika2@med.kindai.ac.jp
准教授：上田 健（Takeshi Ueda）
Associate Professor：Takeshi Ueda
Education
| 2005 | Ph.D., Graduate School of Medicine, Osaka University (Supervisor： Dr. Shigekazu Nagata) |
|---|---|
| 1996 | M.D., School of Medicine, Osaka University, Japan |
Work experience
| 2019-present | Associate Professor, Department of Biochemistry Kindai University Faculty of Medicine |
|---|---|
| 2016-2019 | Instructor, Department of Biochemistry Kindai University Faculty of Medicine |
| 2010-2016 | Assistant Professor, The Research Institute for Radiation Biology and Medicine, Hiroshima University, Japan |
| 2006-2010 | Postdoctoral fellow, Ontario Cancer Institute |
| 2005-2006 | Research Fellow, Japan Science and Technology Agency |
Selected publications
Ueda T, Nakata Y, Yamasaki N, Oda H, Sentani K, Kanai A, Onishi N, Ikeda K, Sera Y, Honda Z, Tanaka K, Sata M, Ogawa S, Yasui W, Saya H, Takita J, Honda H. ALK R1275Q perturbs extracellular matrix, enhances cell invasion, and leads to the development of neuroblastoma in cooperation with MYCN. Oncogene 2016
Ueda T, Nakata Y, Nagamachi A, Yamasaki N, Kanai A, Sera Y, Sasaki M, Matsui H, Honda Z, Oda H, Wolff L, Inaba T, Honda H. Propagation of trimethylated H3K27 regulated by polycomb protein EED is required for embryogenesis, hematopoietic maintenance, and tumor suppression. Proc Natl Acad Sci U S A 2016
Ueda T, Nagamachi A, Takubo K, Yamasaki N, Matsui H, Kanai A, Nakata Y, Ikeda K Konuma T, Oda H, Wolff L, Honda Z, Wu X, Helin K, Iwama A, Suda T, Inaba T, Honda H. Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and upregulation of Nsg2. Blood 2015
Berger T, Ueda T, Arpaia E, Chio II, Shirdel EA, Jurisica I, Hamada K, You-Ten A, Haight J, Wakeham A, Cheung CC, Mak TW. Flotillin-2 deficiency leads to reduced lung metastases in a mouse breast cancer model. Oncogene 2013
Ueda T, Sanada M, Matsui H, Yamasaki N, Honda ZI, Shih LY, Mori H, Inaba T, Ogawa S, Honda H. EED mutants impair polycomb repressive complex 2 in myelodysplastic syndrome and related neoplasms. Leukemia 2012
Ueda T, Sasaki M, Elia AJ, Chio II, Hamada K, Fukunaga R, Mak TW. Combined deficiency for MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) delays tumor development. Proc Natl Acad Sci U S A 2010
Ueda T, Watanabe-Fukunaga R, Ogawa H, Fukuyama H, Higashi Y, Nagata S, Fukunaga R. Critical role of the p400/mDomino chromatin-remodeling ATPase in embryonic hematopoiesis. Genes Cells 2007
Ueda T, Watanabe-Fukunaga R, Fukuyama H, Nagata S, Fukunaga R. Mnk2 and Mnk1 are essential for constitutive and inducible phosphorylation of eukaryotic initiation factor 4E but not for cell growth or development. Mol Cell Biol 2004
