377-2 Ohno-Higashi, Osaka-Sayama, Osaka 589-8511, Japan
Tel +81-72-366-0221
Fax +81-72-366-0245
E-mail seika2@med.kindai.ac.jp
助教：古室 暁義(Akiyoshi Komuro)
Lecturer：Akiyoshi Komuro
Education
| 2007 | Ph.D., Department of Molecular Pathology, Graduate School of Medicine, The University of Tokyo (Supervisor: Dr. Kohei Miyazono) |
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| 2003 | M.S., Department of Biological Science, Graduate School of Bioscience, Tokyo Institute of Technology, Japan |
| 2001 | BSc., School of Bioscience, Tokyo Institute of Technology, Japan |
Work experience
| 2020-present | Lecturer, Department of Biochemistry Kindai University Faculty of Medicine |
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| 2015-2020 | Assistant Professor, Department of Biochemistry Kindai University Faculty of Medicine |
| 2010-2015 | Project Researcher, Department of Molecular Pathology, Graduate School of Medicine, The University of Tokyo, Japan |
| 2008-2010 | Postdoctoral Fellow, Helen Diller Family Comprehensive Cancer Center, Department of Neurological Surgery, UCSF （Supervisor: Dr. Gabriele Bergers） |
Selected publications
Komuro A, Raja E, Iwata C, Soda M, Isogaya K, InoY, Todo T, Aburatani H, Suzuki H, Ranjit M, Morikawa M, Natsume A, Mukasa A, Saito N, Okada H, Mano H, Miyazono K, Koinuma D.: Identification of a novel fusion gene HMGA2-EGFR in glioblastoma. International Journal of Cancer. 142(8) 1627-1639. (2018)
Raja E, Komuro A, Tanabe R, Sakai S, Ino Y, Saito N, Todo T, Morikawa M, Aburatani H, Koinuma D, Iwata C, Miyazono K.: Bone morphogenetic protein signaling mediated by ALK-2 and DLX2 regulates apoptosis in glioma-initiating cells. Oncogene. 36(35):4963-497. (2017)
Tong KI, Ota K, Komuro A, Ueda T, Ito A, Koch AC, Okada H.: Attenuated DNA damage repair delays therapy-related myeloid neoplasms in a mouse model. Cell death & disease. 7(10):e2401. (2016)
Kawabata KC, Ehata S, Komuro A, Takeuchi K, Miyazono K.: TGF-b-induced apoptosis of B-cell lymphoma Ramos cells through reduction of MS4A1/CD20.
Oncogne. 32 (16), 2096-2106. (2013)
Johansson E, Komuro A, Iwata C, Hagiwara A, Fuse Y, Watanabe A, Morishita Y, Aburatani H, Funa K, Kano MR, Miyazono K: Exogenous introduction of tissue inhibitor of metalloproteinase 2 reduces accelerated growth of TGF-β-disrupted diffuse-type gastric carcinoma. Cancer Sci. 101 (11): 2398-2403. (2010)
Komuro A, Yashiro M, Iwata C, Morishita Y, Johansson E, Matsumoto Y, Watanabe A, Aburatani H, Miyoshi H, Kiyono K, Shirai Y, Suzuki IH, Hirakawa K, Kano RM, Miyazono K.: Diffuse-Type Gastric Carcinoma: Progression, Angiogenesis, and Transforming Growth Factor β Signaling. J Natl Cancer Inst. 101(8): 592-604. (2009)
Ikushima H, Komuro A, Isogaya K, Shinozaki M, Hellman U, Miyazawa K, Miyazono K.: An Id-like molecule, HHM, is a synexpression group-restricted regulator of TGF-beta signaling. EMBO J. 27: 2955-2965. (2008)
Komuro A, Imamura T, Saitoh M, Yoshida Y, Yamori T, Miyazono K, Miyazawa K.: Negative Regulation of Transforming Growth Factor-b (TGF-b) Signaling by WW Domain-containing Protein 1 (WWP1). Oncogene. 23: 6914-6923. (2004)
