2023 研究成果

2023 研究成果

2023年

MYC/glutamine dependency is a therapeutic vulnerability in pancreatic cancer with deoxycytidine kinase inactivation-induced gemcitabine resistance
Dash S, Ueda T, Komuro A, Amano H, Honda M, Kawazu M, Okada H.
Molecular Cancer Research (2023) 21 (5): 444–457 (online publication Feb 9, 2023)

https://aacrjournals.org/mcr/article/doi/10.1158/1541-7786.MCR-22-0554/716490/MYC-glutamine-dependency-is-a-therapeutic

MBTD1 preserved adult hematopoietic stem cell pool size and function
Takubo K, Htun PW, Ueda T, Sera Y, Iwasaki M, Koizumi M, Shiroshita K, Kobayashi H, Haraguchi M, Watanuki S, Honda ZI, Yamasaki N, Nakamura-Ishizu A, Arai F, Motoyama N, Hatta T, Natsume T, Suda T, Honda H.
Proc Natl Acad Sci USA 2023 Aug 8; 120(32):e22036860120.doi:10.1073/pnas. 2206860120 Epub 2023 Jul. 31

https://www.pnas.org/doi/10.1073/pnas.2206860120?url_ver=Z39.88-2003&rfr_id=ori

One-carbon metabolizing enzyme ALDH1L1 influences mitochondrial metabolism through 5-aminoimidazole-4 carboxamide ribonucleotide accumulation and serine depletion, contributing to tumor suppression
Sasaki M, Yamamoto K, Ueda T, Irokawa H, Takeda K, Sekine R, Itoh F, Tanaka Y, Kuge S, Shibata N.
Sci Rep. 2023 Aug 18; 13(1):13486.doi:10.1038/s41598-023-38142-5

https://www.nature.com/articles/s41598-023-38142-5

A novel in vivo model of ureteral fibrosis induced by calcium oxalate beads in C57BL/6J mice
Watanabe M, Ando R, Sugisawa R, Sasaki N, Iwai S
Urolithiasis 51(1):119. doi: 10.1007/s00240-023-01491-x

https://link.springer.com/article/10.1007/s00240-023-01491-x