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研究成果 - 近畿大学医学部生化学教室

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研究概要

2018年

JMJD2B/KDM4B inactivation in adipose tissues accelerates obesity and systemic metabolic abnormalities
Kang C, Saso K, Ota K, Kawazu M, Ueda T, Okada H
Genes Cells (online 2 August, 2018)

2017年

The H3K27 demethylase, Utx, regulates adipogenesis in a differentiation stage-dependent manner
Ota K, Tong KI, Goto K, Tomida S, Komuro A, Wang Z, Nishio K, Okada H
PLOS ONE 12(3): e0173713

Identification of a novel fusion gene HMGA2-EGFR in glioblastoma
Komuro A, Iwata C, Soda M, Isogaya K, Ino Y, Todo T, Aburatani H, Suzuki H, Ranjit M, Natsume A, Saito N, Okada H, Mano H, Miyazono K, Daizo K
International Journal of Cancer (online 29 November, 2017)

2016年

Attenuated DNA damage repair delays therapy-related myeloid neoplasms in a mouse model
Tong KI, Ota K, Komuro A, Ueda T, Ito A, Koch AC, Okada H
Cell death & Disease 7(10):e2401

Deletion of JMJD2B in neurons leads to defective spine maturation, hyperactive behavior and memory deficits in mouse
YT Fujiwara K, Fujita Y, Kasai A, Onaka Y, Hashimoto H, Okada H, Yamashita T
Transl Psychiatry. 6 (e766)

Loss of survivin in intestinal epithelial progenitor cells leads to mitotic catastrophe and breakdown of gut immune homeostasis
Martini E, Wittkopf N, Gunther C, Leppkes M, Okada H, Watson AJ, Podstawa E, Backert I, Amann K, Neurath MF, Becker C.
Cell reports 14 (5), 1062-1073

2015年

The Role of Histone Demethylase KDM4B in Myc Signaling in Neuroblastoma
Yang J, AlTahan AM, Hu D, Wang Y, Cheng PH, Morton CL, Qu C, Nathwani AC, Shohet JM, Fotsis T, Koster J, Versteeg R, Okada H, Harris AL, Davidoff AM.
J Natl Cancer Inst. 107 (6)

2014年

Histone Lysine Demethylase and Human Diseases (review)
Okada H
ACTA MEDICA KINKI UNIVERSITY 39 (1), 1-10